MLB ready to suspend A-Rod, Ryan Braun, and others

The hammer may be coming down in what could be by far the biggest crackdown yet on steroids in Major League Baseball.

According to ESPN, the league may hand down 100-game suspensions to as many as 20 players connected to a suspicious Miami anti-aging clinic. The list includes big names like former MVP Ryan Braun of The Brewers, and Alex Rodriguez, who is in the middle of the richest contract in baseball history - 10 years for $ 275 million. The New York Yankees handed him the contract back in 2007, in hopes that he would have a clean, and very lucrative pursuit of the all-time home run record.

The MLB has no positive drug tests, but appears ready to hand down the serious penalties without them.

CNN's Rachel Nichols reports for "The Lead" in the video above.