Anchored by Jake Tapper, The Lead airs at 4 p.m. ET on CNN.
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(CNN) – A Malaysia Airlines passenger jet crashed in eastern Ukraine on Thursday, prompting swift accusations from Ukrainian officials that "terrorists" shot down the aircraft.
The Boeing 777 carrying 295 people went down near the town of Torez in the Donetsk region of eastern Ukraine as it flew at about 10,000 meters (nearly 33,000 feet) on the way from Amsterdam to Malaysia.
No survivors have been found.
The toll will be difficult for families and loved ones in Malaysia, the Netherlands, and elsewhere to bear.
That someone did it on purpose has serious ramifications, beyond the human tragedy, when it comes to world events.
CNN's Jake Tapper and Jim Sciutto report in the video above.