Anchored by Jake Tapper, The Lead airs at 4 p.m. ET on CNN.
Rep. Tulsi Gabbard, D-Hawaii, on possibly increasing duration of the Ebola incubation.
New York (CNNMoney) – Diane Sawyer will step down from ABC's flagship nightly newscast, "World News," in August, ABC said Wednesday.
David Muir, the weekend "World News" anchor, will replace her starting September 2.
The announcement ends months of speculation about a transition at ABC's anchor desk.
(CNN) – Rep. Charlie Rangel, D-New York, who was first elected in 1971, claimed victory in what he says is his last race, looking like he'll survive a second straight narrow victory against the same opponent he faced two years ago when he barely kept his political career alive.
Rangel blamed the changing district for his slim margins of victory.
"About 20% of my district now goes to a different county," said Rangel. "My opponent was apparently more popular in that district than I thought he would be."
(CNN) - The deadly Ebola virus outbreak in West Africa has hit "unprecedented" proportions, according to relief workers on the ground.
"The epidemic is out of control," Dr. Bart Janssens, director of operations for Doctors Without Borders, said in a statement.
There have been 567 cases and 350 deaths since the epidemic began in March, according to the latest World Health Organization figures.
(CNN) – She's facing a myriad of attacks from the right, but former secretary of state Hillary Clinton says she does not need her husband standing up for her.
"My husband was very sweet today, but I don't need anybody to defend my record, I think my record speaks for itself," Clinton told PBS Newshour.
She's referring to the former president's fierce defense of her assertion that the family was "dead broke" when they left the White House.
Washington (CNN) – White House officials are not disputing reports that both Syria and Iran are conducting military operations in Iraq to contain the ISIS threat.
That may be making for some of the strangest possible bedfellows when it comes to dealing with Iraq
CNN's Jim Acosta reports.