Anchored by Jake Tapper, The Lead airs at 4 p.m. ET on CNN.
A look at Obama's immigration plan. Plus, how long Takata knew of problems with its airbags.
Sen. John McCain, R-Arizona, said conservative Republican attempts to defund Obamacare will prove fruitless.
"In the United States Senate, we will not repeal or defund Obamacare. We will not. And to think we can is not rational," McCain said Thursday on “The Lead with Jake Tapper.”
Republicans Sen. Ted Cruz suggested he might filibuster if defunding Obamacare is not tied to funding the government. But McCain said the party does not have 67 Republican votes in the Senate which would be required to override a presidential veto.
"To somehow think we are going to defund it is simply not going to happen at this time, and it will, in my opinion, as it did before, harm the American people's view of the Republican party," said McCain.
For more of this interview with Sen. John McCain, including his views on Russian President Vladimir Putin, watch the video above.